T2 weighted FLAIR sequences are typically used for the evaluation of which condition?

T2 weighted Fluid-Attenuated Inversion Recovery (FLAIR) sequences are particularly useful in the evaluation of white matter disease due to their sensitivity in highlighting changes and abnormalities in the brain's white matter. FLAIR sequences are designed to suppress signals from fluids such as cerebrospinal fluid (CSF), making it easier to identify lesions, edema, or other pathology in the cerebral tissues. This is particularly relevant in assessing conditions such as multiple sclerosis, small vessel disease, and other demyelinating disorders that predominantly affect the white matter.

By suppressing CSF signal, FLAIR imaging reveals hyperintensities that may indicate pathology in the white matter, allowing for a clearer visualization of lesions that are otherwise obscured in standard T2-weighted images. This quality makes FLAIR an essential tool in neuroimaging for diagnosing and monitoring various white matter pathologies.